Protein folding simulations in a deformed energy landscape
Department of Physics Michigan Technological University Houghton, MI
Published online: 13 August 2012
A modified version of stochastic tunneling, a recently introduced global optimization technique, is introduced as a new generalized-ensemble technique and tested for a benchmark peptide, Met-enkephalin. It is demonstrated that the new technique allows to evaluate folding properties and especially the glass temperature Tg of this peptide.
PACS: 05.10.-a – Computational methods in statistical physics and nonlinear dynamics / 87.16.Ac – Theory and modeling; computer simulation
© EDP Sciences, Società Italiana di Fisica, Springer-Verlag, 1999