Eur. Phys. J. B 54, 131-136 (2006)
https://doi.org/10.1140/epjb/e2006-00417-1

Vectorial representation of single- and multi-domain protein folds

Institut für Festkörperphysik, Technische Universität Darmstadt, Hochschulstr. 6-8, 64289,  Darmstadt, Germany

Corresponding author: ^a porto@fkp.tu-darmstadt.de

Received: 13 April 2006
Revised: 9 October 2006
Published online: 8 December 2006

Abstract

We discuss a vectorial representation applicable to both single- and multi-domain protein folds. This generalized vectorial representation is essentially identical to the previously described vectorial representation for single-domain proteins folds when applied to these, but allows for the additional consistent representation of multi-domain structures. We show that the generalized vectorial representation enables the accurate analytical prediction of site-specific amino acid distributions for both single- and multi-domain protein folds, similarly as the previously described vectorial representation does for single-domain folds.