Simple models of proteins with repulsive non-native contacts
Institute of Physics, Polish Academy of Sciences,
Al. Lotnikow 32/46, 02-668 Warsaw, Poland
Revised: 13 October 1999
Published online: 15 April 2000
The Go model is extended to the case when the non-native contact energies may be either attractive or repulsive. The folding temperature is found to increase with the energy of non-native contacts. The repulsive non-native contact energies may lead to folding at T=0 for some unusual two-dimensional sequences and to reduction in complexity of disconnectivity graphs for local energy minima.
PACS: 87.10.+e – General theory and mathematical aspects / 87.15.By – Structure and bonding
© EDP Sciences, Società Italiana di Fisica, Springer-Verlag, 2000